12
February

Unlocking the Power of Liposomes for Improved Health and Wellness

Liposomes are spherical marvels of nature, composed of a lipid bilayer that envelops an inner compartment. Their unique structure has been a subject of fascination for scientists, and it is no wonder why. The lipid bilayer of these microscopic wonders enables the entrapment and transport of a multitude of drugs, enzymes, and nutrients, making them a multi-faceted tool in the ever-expanding field of medicine and health. They are truly a beacon of hope in the quest for improved health and wellness.

What are Liposomes?

These nanoscale spheres are composed of a lipid bilayer that encases a central compartment, much like the cell membranes that envelop our own cells. This unique architecture enables the entrapment and transport of a wide array of substances, ranging from drugs, enzymes, and nutrients. Science has long been intrigued by these wonders of nature and has deemed them a promising tool in the ever-evolving fields of medicine and health. Their superiority over traditional drug delivery systems only adds to their allure and potential in improving our overall well-being.

The Benefits of Liposomes

The beauty of this design lies in its ability to safeguard entrapped substances from degradation, all while precisely targeting specific cells or tissues in the body. The lipid bilayer serves as an impenetrable shield, preserving the integrity of the substance as it travels through the body. This translates to a higher level of efficacy, as the substance arrives at its intended destination in its active form, ready to carry out its intended purpose with potency. It’s a true testament to the brilliance of nature’s design.

Liposomes are seriously cool! They’ve got this special skill of taking drugs that are hard to dissolve and making them more effective. By encapsulating these drugs in their inner compartment, liposomes increase their solubility and bioavailability. This means we get more of the drug where it needs to go, and with fewer side effects.

Liposomes in Health and Wellness

Liposomes have proven to be a versatile tool in the realm of health and wellness, lending their unique properties to various applications. In the world of skincare, these nanoscale structures have been harnessed to deliver active ingredients such as vitamins and antioxidants directly to the skin, enhancing its health and reducing the signs of aging. The oral cavity too, has benefitted from the use of liposomes, as they have been employed to deliver antibiotics, antimicrobials, and enzymes to improve oral hygiene and reduce the threat of gum disease. And finally, liposomes have been utilized in nutrient delivery, bringing vital vitamins, minerals, and other nutrients to the body and thereby promoting overall health and well-being.

Liposomes in Medicine

Liposomes have proven to be a versatile carriers not just in enhancing health and wellness, but also in the realm of medicine. These tiny spherical structures, composed of a lipid bilayer and an inner compartment, have been employed in the delivery of drugs to targeted cells, the visualization of bodily tissues through imaging, and even the detection of biomarkers in diagnostics. The unique properties of the lipid bilayer have made liposomes a valuable tool in a multitude of medical applications.

Liposomes: The Future of Health and Wellness

Liposomes have the potential to revolutionize the field of medicine and health, providing a more effective alternative to traditional drug delivery methods. As we delve deeper into the intricacies of these tiny spherical structures, it becomes clear that they hold great promise for the future. With continued exploration and technological advancements, the potential applications of liposomes are vast and varied, and we can only imagine what the future may hold.

Reputable health supplements brands such as Renuebyscience are already adopting liposomes for their NAD+ complex supplements, you should check them out if you are interested in learning more about liposomes, You can even get a discount that Renuebyscience is offering for a limited time on various supplements.

Liposomes have already proven themselves to be a valuable asset in various sectors of the health and wellness industry, be it for cosmetic purposes, oral health, or even delivering drugs and diagnosing conditions. The properties of this unique structure make them an excellent tool, capable of protecting the enclosed substance, targeting specific cells and tissues, and enhancing the solubility and efficacy of drugs. Undoubtedly, with further research and advancements, the role of liposomes in enhancing the well-being of people globally will only become more prominent.

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3
January

The Importance of a Healthy Lifestyle on Longevity

Living a healthy lifestyle is important for a variety of reasons. It can help you feel your best, maintain a healthy weight, and reduce your risk of chronic diseases such as heart disease, diabetes, and cancer. While it may seem like a daunting task to make significant changes to your lifestyle, there are small steps you can take every day to live a healthier life.

Diet

One of the most important aspects of living a healthy lifestyle is paying attention to your diet. This means filling your plate with a variety of nutrient-dense foods such as fruits, vegetables, whole grains, and lean proteins. It also means being mindful of your portion sizes and limiting your intake of added sugars and unhealthy fats.

One way to improve your diet is to plan your meals and snacks in advance. This can help you make healthier choices and avoid the temptation of fast food or processed, sugary snacks. It’s also a good idea to keep a variety of healthy foods on hand, so when you’re feeling hungry you have a healthy option readily available.

Exercise

Incorporating regular physical activity into your routine is another important aspect of living a healthy lifestyle. Aim for at least 30 minutes of moderate-intensity activity, such as brisk walking or cycling, every day. If you’re short on time, you can break up your activity into shorter, 10-minute increments throughout the day.

In addition to the numerous physical benefits of exercise, it can also improve your mental health and help reduce stress. So, try to find activities you enjoy, whether it’s a sport, a workout class, or just going for a hike in nature.

Sleep

Getting enough sleep is crucial for both physical and mental health. Aim for 7-9 hours of sleep per night, and create a bedtime routine that helps you relax and unwind before going to sleep. This might include reading a book, taking a warm bath, or practicing relaxation techniques such as deep breathing or meditation.

Avoid screens, such as phones and laptops, for at least an hour before bed, as the blue light they emit can disrupt your body’s natural sleep-wake cycle. It’s also a good idea to create a sleep-friendly environment by keeping your bedroom cool, dark, and quiet, and using a comfortable mattress and pillows.

Stress management

Chronic stress can have negative impacts on both your physical and mental health. It’s important to find ways to manage stress in a healthy way. This might include exercising, meditating, spending time with loved ones, or engaging in a hobby you enjoy.

It’s also important to prioritize self-care, which might include getting regular massages or haircuts, taking breaks to relax, and saying no to activities that you don’t have the time or energy for. Remember, it’s okay to take some time for yourself and prioritize your own well-being.

Conclusion

By making small changes to your diet, exercise routine, sleep habits, and stress management techniques, you can improve your overall health and well-being. Don’t be afraid to make these changes gradually, and be kind to yourself if you slip up. Remember, living a healthy lifestyle is a journey, not a destination, and it’s important to celebrate your progress along the way.

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27
July

The surprising benefits of NAD+

NAD+ is needed for gene maintenance and mitochondrial performance. However, as we grow older, the level of NAD+ steadily diminishes which leads to age-related conditions. Taking NAD+ Supplements displays healthy advantages in the body which are listed below.

Neurodegeneration

Aging process is the main reason for numerous neurological conditions such as Alzheimer’s and Parkinson’s diseases. In a study carried on mice with Alzheimer’s, it was discovered that increasing the NAD+ level can reduce the protein accumulation which harms cell communication. By boosting NAD+, cognitive development is improved and it maintains the brain cells when there is a lack of blood flow to the brain. The current research on animal modules displays new possibilities of healthy brain aging through NAD+. 

metabolic repair

Metabolic conditions

Obesity is the notorious disease of today’s world and it is also the prime cause of diabetes. The administration of NAD+ in mice proved that it can avoid age-related and diet-related weight gain. Moreover, NAD+ boosted the exercise stamina of mice, even in old mice. In other studies reviewed on Alivebyscience, the diabetes effect was reversed in the female mice leading to metabolic repair. 

Heart function

The vessels inside the heart have to be elastic so that heartbeats can be smooth. However, the elasticity of blood vessels decreases with age which results in high blood pressure. This condition can lead to blocked vessels and a swollen heart. But with the supplements of NAD+, the heart is shielded from aging and cardiac performance is boosted. In mice, giving NAD+ prevented injuries on the organ due to the insufficient blood flow. Another research revealed that NAD+ protects mice from heart swelling. 

Aging

Popular for being a crucial group of proteins, sirtuins protect animals and plants from aging and illness. The stimulus behind the working of sirtuins is NAD+. Just like a vehicle can not drive without the fuel, sirtuins cannot function without the presence of NAD+. The outcome of research displays that boosting the NAD+ levels in the body activates sirtuins and elongates the lifetime of mice, yeast and worms. 

Muscle stability

Mitochondria is the powerhouse of animal cells. It is the responsibility of NAD+ to regulate healthy mitochondria and maintain its energy output. By increasing the NAD+ level in muscles of mice, their fitness and mitochondria performance were improved. The research also showcased that mice taking NAD+ supplements are smarter and have the ability to run faster on the treadmill. This is called high exercise capacity.

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25
November

What are the Best NMN Supplements For Anti-Aging?




The salvage/recycling pathway for NAD+ biosynthesis from nicotinamide riboside (NR) in manNR, taken in to the body, can be converted to nicotinamide mononucleotide (NMN) by one of two highly conserved NR kinases in the cytoplasm (pathway 1a). NAM (nicotinamide) can also be converted by NMN synthetase to NMN (pathway 1b). NMN is further converted to NAD+ by the action of one of three adenylyltransferases (NMNAT1‐3) that also acts on NaMN (nicotinic acid mononucleotide) to produce NaAD+ (nicotinic acid adenine dinucleotide). The latter is subsequently converted by NAD synthase to NAD+. Nicotinic acid (Na) feeds into the pathway through conversion to NaMN by Na phosphoribosyltransferase (pathway 1c). Tryptophan is the de novo precursor of NAD+ that also feeds into NaMN synthesis via a multistep pathway (2) described in Bogan and Brenner (2008). Robert N Lightowlers, and Zofia MA Chrzanowska‐Lightowlers EMBO Mol Med. 2014;emmm © as stated in the article, figure or figure legend.

Definition of Anti-Aging

Anti-Aging is the practice, procedure, or a dietary regimen by which the natural process of aging is slowed down for an indefinite period of time. This is done by utilizing natural dietary sources or medical procedures. Even though aging occurs to everyone and it is known as an unavoidable law of nature, no one wants to go through it and get white hair or wrinkles. This is the reason why a great deal of exploration both in scientific and medical areas has been directed to understand how aging symptoms can be slowed down. A fruitful formula for anti-aging is based on a naturally occurring organic molecule “Nicotinamide Mononucleotide” which is commonly known as NMN.

How does NMN slow down aging?

Nicotinamide Mononucleotide is actually is a scientific term for a molecule which originates from Vitamin B. It is found in all living things and can be consumed in the form of supplements or pills. This molecule or all the more explicitly, nucleotide, improves and directs a lot of cycles in the body which are crucial to digestion and overall health. For instance, the benefits of glucose tolerance, expanded insulin creation and removing diabetes are some of the main things NMN is assigned for. Furthermore, the assembling of new cells,

re-establishing crucial proteins and avoiding oxidation (which initiates the aging process) is properly done by Nicotinamide Mononucleotide. This is the reason why it is hailed as the major organic molecule which protects the body against aging and aging symptoms. Direct use of the nucleotide or taking it in the form of drug both are accessible. Following are the best anti-aging supplementation in the market.

1-  Infinite Age NMN, NAD Precursor Supplement

These powder capsules are ideal for turning on the genes which prolong the life expectancy. In addition, it levels up the production of energy, blood flow and heart and brain health, immune system, endurance and metabolism. By fixing DNA and decreasing anxiety, you will naturally feel younger and healthier. This medication offers the availability of NMN molecules in 99.5% purity. Both life span and well-being is improved in light of the fact that the Infinite Age supplement increases the percentage of NAD+ in the blood flow. Muscle strength and brain health are the main objectives of the medicine as these aspects are

influenced the most by aging. The anti-aging gene called Sirtuins is boosted in order to increase the lifespan.

2-  GeneX Formulas NMN capsules

This brand GeneX is famous in the production of NMN aging Supplements. Moreover, their medicines are available in both powder and capsules. The formulas of this brand make the veins grow stronger which results in a smooth blood flow. These vegetarian pills are available in the 125 mg dosage. They improve the endurance and vitality levels. The muscle development is initiated as well which improves health. The weight that is gained through old age is decreased and additionally, insulin sensitivity is enhanced.

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21
January

The Use of Fisetin for Brain Protection 

Cerebrovascular and neurodegenerative disease is the leading cause of death in most cases of brain illnesses. Oxidative stress leads to the death neural death in cases such as stroke and oxidative reactions that are in arteriosclerosis, the primary pathological condition leading to stroke.

The neuroprotective effects of senolytics therapies show that flavonoids induce the growth of neurite in brain cells. Which also indicate the differentiation in neurons. Fisetin is the most effective flavonoid that promotes neurite growth. Investigating if the activation of cells by Fisetin is needed for their growth, researchers use three unrelated inhibitors. A similar effect is noted when treatment is done with the same inhibitors on Fisetin controlled growth.

There is consistency with previous studies showing how these activations provide neuroprotection while at the same time accelerate neural cell death. Moreover, reduced signaling in the cells that activate normal brain cell activities is observed in patients who have Huntington’s disease. This signals that the activation of some cells may introduce a new senolytic and therapeutic approach to tame neural dysfunction.

In relation to the mediated neurotrophic effects of Fisetin, most research data indicate that Fisetin does not enhance the exertion of the inhibitory effect on cell signaling. Fisetin suppresses the activation of some inhibitors in lipopolysaccharide. A comparative study involving apigenin, luteolin, and Fisetin was done as a study of their inhibitory effects and transcription activation. Evidence from this study indicates Fisetin suppress the invasion and migration of the lung cancer cells through inhibition of some cell activity. Given these outcomes that show some conflicting results is an indicator that more studies need to be done so that a conclusive report on the dual effects of Fisetin on brain cell signals and presentation of the mechanisms taking place on the healthy cells and cancer cells.

Fisetin has been used to show the effect pathways involved in the maintenance of neuronal functions during aging. It acts an antioxidant, maintains the mitochondrial function when oxidative stress is increasing, offers anti-inflammatory protection against microlial cells and inhibits the activity of 5-lypoxygenase  that show how Fisetin can reduce the age-related decline in brain functions.

The ability of Fisetin to safeguard neural dysfunction was examined in three different models of Huntington’s disease:

  1. In cells that express mutant Huntington protein after the induction of inducible promoter
  2. In Drosophila expressing mutation of Httex1
  3. In the mouse model

All the three instances show that Fisetin reduces the impact of mutant huntingtin protein in all three observations above and are useful in the treatment of HD by reducing activation cells related to HD mutant protein.

As an antidepressant, Fisetin and its mechanism were observed in previous studies. Data coming from despair tests on mouse models show that Fisetin dose can inhibit movement time when seen in behavioral experiments. The Fisetin doses may affect the cell movement and response and do not affect locomotor activity.

More studies on Fisetin and its noradregic and sarotergenic properties. The higher dose of Fisetin counteracts the hypothermia induction by reserpine and leads to an increase in serotonin and noradrenaline levels in the frontal cortex and hippocampus. This increase is enough proof that the antidepressant effect of Fisetin is due to the regulation of central serotonin levels.

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12
December

What Is the Subconscious Mind?

Woman in front of bathroom mirror with her alter ego in the reflection

Explaining the subconscious can be challenging. The greatest minds of previous generations, like Sigmund Freud and Carl Jung, spent much of their careers trying to wrap their heads around the difference between the conscious mind and the subconscious mind.

Even today, you’ll run across psychiatrists who insist on dubbing it the “unconscious mind” and who take a more limited view of the concept as it applies to therapeutically beneficial disciplines.

But the truth is that the subconscious mind is real, it is vast, and more importantly, it is under our control.

The Birth of the Subconscious

The subconscious has always been with us—the human mind cannot function without it. But how did our understanding of the subconscious come about?

The word “subconscious” is an anglicization of the French word “subconscient,” as coined by the psychologist Pierre Janet. Janet theorized that underneath the layers of critical components and functions of the conscious mind lay a powerful awareness that he described as the subconscious mind.

Illustration of Sigmund Freud with patientFreud first used the term in 1893 to describe associations and impulses that are not accessible to consciousness, while Jung argued that—because there is a limit to what is held in conscious focal awareness—there must be an alternative storehouse of one’s knowledge and experience.

In other words, the subconscious refers to both mental processing that occurs below awareness and content that resides below conscious awareness but that is capable of becoming conscious again. This back-and-forth between subconscious and conscious awareness is why a person under hypnosis can often recall events from years ago with perfect clarity, even if they don’t consciously retain that knowledge from day to day.

But what does the subconscious do for the human body?

What the Subconscious Does for People

First of all, the subconscious mind and the functions it controls—such as breathing, digestion, body temperature and the nervous system—keeps us alive.

Through your autonomic nervous system, the subconscious maintains equilibrium among the hundreds of chemicals in your body. This keeps your engine running and your bodily functions in harmony.

The function of the subconscious mind, other than the autonomic functions mentioned above, is to store and retrieve data. The best analogy for all the other functions that the subconscious serves is to imagine it as a vast memory bank. The subconscious mind stores all of your previous life experiences, memories, skills, your beliefs about the world and your sense of self. Its capacity is virtually unlimited and it permanently stores everything that has ever happened to you.

Hypnosis is an effective therapeutic strategy because it taps into the subconscious. It isn’t triggering a conscious memory that you carry with you on a day-to-day basis. Rather, hypnosis speaks directly to the subconscious, which can absorb or elevate memories as they are needed.

Underneath all that raising and absorbing of memories, your subconscious is working day and night to maintain a balance. And that balance is there to establish a pattern of behavior and response to stimuli that is consistent with your emotionalized thoughts, hopes and desires. It’s a kind of homeostasis that keeps you thinking and acting in a manner consistent with what you have done and said in the past.

We should note here that your subconscious mind is subjective. It does not think or reason independently; it merely obeys the commands that it receives from your conscious mind.

The conscious mind is responsible for logic, calculations, and decisions—all forms of action that you perform while you are awake and conscious. And during hypnotic intervention, the subconscious mind is particularly open to suggestion.

Here’s the rub: because your subconscious works so hard to maintain the pattern of behaviors that it has come to establish as your “normal” behavior, unhealthy habits can be very hard to break without outside intervention. Your subconscious mind causes you to feel emotionally and physically uncomfortable when you attempt to change those established patterns of behavior.

One reason disciplines like yoga, hypnosis and cognitive-behavioral therapy work as psychological interventions is in part because they speak directly to the subconscious.

The good news is that when you learn to purposefully create new patterns that are fully absorbed by the subconscious, you can harness the power of habit and suggestion to instill new comfort zones to which your subconscious mind will adapt.

Creative ideas emerging from seated woman

The Path to Change Runs Through the Subconscious

There are lots of metaphors for the subconscious mind: the submerged part of an iceberg, the bank in which we deposit memories, and the “engine” that keeps our bodies running.

The subconscious uses emotions, memories, core values and beliefs as filters to sift through an otherwise incomprehensible amount of external and internal stimuli, and it condenses that information to a size that you can internalize and make sense of. What you perceive as “reality” is the result of all those factors.

The subconscious is also the source of creativity, intuition, inspiration, inner acceptance, interconnectedness and what eastern religions call “enlightenment.” And, just like your body has defenses against physical injuries, your subconscious provides defenses against emotional shocks and injuries.

The conscious and the subconscious mind make a great team when you learn to use them together. The conscious mind efficiently handles tasks and engagements before sending them off the subconscious to put away, while the subconscious can offer feedback and messages about the task in the form of emotions delivered to the conscious mind.

By learning how to make the best use of these two states of consciousness, you can improve skills, absorb healthy suggestions, and have much more control over your emotions.

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