Boost brain, liver and muscle function with Doctor’s Best – Basis supplement. By providing nicotinamide riboside (NR), a nutrient which is found in certain food, this niagen supplement improves overall health by starting at the cell level. NR is a metabolic starter for nicotinamide adenine dinucleotide (NAD) and is vital for healthy energy levels and metabolism.

• Best Niagen is 100 percent science based
• Good choice for vegetarians and vegans
• Naturally boost mitochondrial energy production
• Enhances cell functions and cell health
• Helps create energy from glucose (sugars) and fat

Most of the adenosine triphosphate (ATP) found in your body comes from your body processing carbs and glucose. ATP and NAD levels appear to be very much linked together. They seem to sync together. When ATP levels drop, so do NAD levels. This is common when glucose levels drop and when that happens, sirtuins start stop using energy enzymes and start depending on alternative energy sources.

When glucose levels drop too low, the sirtuins start working with cells to produce ATP from fats. Enzymes start to burn more long-chain fatty acids and very-long chain fatty acids in stead of just the short-chain fatty acids. This promotes better fat burning for increased energy.

Should your fats and glucose levels severely drop due to being nutrient-depleted, sirtuins can step in and start burning alcohol (acetate) and proteins (amino acids) to supply ATP.

Mitochondrial Energy

The mitochondria is the super-powerful part of your cells that burns calories from nutrients and generates ATP.

Consumed NR, which is found in cow’s milk and yeast, makes a b-line to your cells. It’s then converted into NAD and is made available to the mitochondria. Sirtuin 3 (SIRT3 for short) and other sirtuins seem to know how much NAD is available and respond accordingly. They ensure ATP that’s needed is produced and they also go on the defense to protect free radical damage to your mitochondria.

That protection is important, because when the mitochondria goes to work burning caloric nutrients and generating ATP, they can also inadvertently create oxygen free radicals that can be harmful. There’s no way to prevent this. But if there are adequate levels of NAD, it will help protect against those free radicals and keep ATP production levels where they need to be.

Cell Function

Among the seven human sirtuin enzymes, SIRT1 is the go-between for your body’s metabolic adaptive responses. It’s what controls metabolic regulation of insulin sensitivity and glucose production. It’s smart.. it knows when NAD levels change and acts accordingly. If free radicals increase, it’ll increase the vital antioxidants to help provide protection from them. In short, SIRT1 is cells best friend and confidant when it comes to stressful times, helping them to adapt, react and stay healthy.

PARP (poly ADP-ribose polymerases) is another NAD dependent group of enzymes. They too know when NAD levels change and they come to the rescue when they sense that DNA, proteins or genes are in danger. CD157 and CD38 are important for calcium levels. ADP-ribose is also similar to PARP.

All together, a great demand for NAD is created. NR supplements are very effective at helping to offset that demand.

Niagen for Boosting Brain Health

Nerve cells are known to be some of the most active cells in your body. They both develop and use energy, leading to an increased demand for NAD. They carry in NR and carry the NrK2 enzyme (nicotinamide riboside kinase 2), creating NAD from NR. As NAD levels rise, so do the amount of enzymes that come to the rescue and relieve stress on the cells.

SIRT1 is well-known to play a vital role in brain health. It’s important for regulating moods. It helps boost the ability to learn, memory and even has an effect on behavior. It enables neuroplasticity, which is your brain’s ability to adapt to changes.

Readily used NAD is known to be available from NR, making NR extremely important for helping your body deal with stress, manage energy and boosting and maintaining overall good health.

Why Choose Doctor’s Best?

Unlike the more expensive options like Basis, Doctor’s Best simply uses only the best ingredients but doesn’t spend $$ advertising everywhere.

Weaving together innovative technology, pure natural ingredients, in-depth research and traditional wisdom means the end product is one of the best we’ve seen.

Usage

Take one veggie capsule twice a day following a meal. Your doctor may recommend a higher dose in some situations.